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Nexium: Contraindications,Side effects,Interaction

January 15th, 2010

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Information About Generic Nexium (Esomeprazole Magnesium)

What is Generic Nexium (Esomeprazole Magnesium)

Working of Generic Nexium (Esomeprazole Magnesium)

Generic Nexium (Esomeprazole Magnesium) Dosage or Administration

Precautions for Taking Generic Nexium (Esomeprazole Magnesium)

Interaction of Generic Nexium (Esomeprazole Magnesium) with Other Drugs

Side effects of Generic Nexium (Esomeprazole Magnesium)

Esomeprazole Magnesium is generic equivalent of Nexium, it is used for treatment of (SGRD) Symptomatic Gastroesophageal Reflux Disease, and healing of Erosive Esophagitis.

Generic nexium prevents or/and treat gastric ulcer, caused as a side-effects of NSAID (Non-steroidal anit-inflammatory) drugs like diclofenac for the treatment of arthritis.

What is Generic Nexium (Esomeprazole Magnesium)

Generic Nexium belong to calss Proton Pump Inhibitor. Generic Nexium is proton pump inhibitor (PPI). Generic nexium (Esomeprazole) reduces descretion of acid in the gastric parietal peritoneumme called H+/K+-ATPase. Although it is the combination R- isomers and S-isomer it is called S-isomer omeprazole. As it inhibits excessive descrtion of acid in stomach it is also indecated for condition Zollinger-Ellison syndrome.

How Generic Nexium Works?

Excess production is the most common reason for Erosive Esophagitis, peptic ulcer and Symptomatic Gastroesophageal Reflux Disease.

Generic nexium is type of PPIs(Proton pump inhibitor) called vacuolar-type which highly inhibits Acid-generating ATPase found in lysozomes of leukocytes and osteoclasts and its activities. Human body produces acid that helps digestive system to digest food. In excessive decrestion of acid condition like Zollinger-Ellison syndrome, acid enters and flows through food pipe which results in heartburn. Nexium produces achiral sulphenamide in acidic compartment which stops formation of such acids.

Excess of acid also cause inflamation on lining of oesophagus (Food pipe). Helicobacter pylori bacteria causes unnecessery acid production in stomach which finally results in peptic ulcer. Nexium along with amoxicillin and clarithromycin have found to be very effective on ulcer in stomch caused when infacted with helicobacter pylori (H. pylori) bacteria.

Generic Nexium (Esomeprazole Magnesium) Dosage or Administration

Generic Nezium is avialable in two strengths, 20mh and 40mg. Daily dose of 20 to 40 mg and can prevent formation of gastric acid.

Overdose

Look for immediate emergency medical aid incase of any side effects listed below…

Intense or low itching on skin anywhere on body (hives)
Short breathing
seizures
Swelling of face
Loosing coordination

Precautions for Taking Generic Nexium (Esomeprazole Magnesium)

Generic nexium should not be taken if the person is hypersensitive to the any of the ingredients chemical compound of generic nexium. Hypersensitive person may get Angioedema and anaphylactic shock.

It is prudent for preganant women not to take generic nexium as no study have been conducted to observe its effects on pregenant women.