Information About Generic Prilosec (Omeprazole)

What is Generic Prilosec (Omeprazole)

Working of Generic Prilosec (Omeprazole)

Generic Prilosec (Omeprazole) Dosage or Administration

Precautions for Taking Generic Prilosec (Omeprazole)

Interaction of Generic Prilosec (Omeprazole) with Other Drugs

Side effects of Generic Prilosec (Omeprazole)

Omeprazole is generic equivalent of Prilosec, it is used for treatment of active duodenal ulcer, gastroesophageal reflux disease (GERD), including erosive esophagitis and symptomatic GERD; long-term treatment of pathologic hypersecretory conditions (eg, Zollinger-Ellison syndrome, multiple endocrine adenomas, systemic mastocytosis); to maintain healing of erosive esophagitis; in combination with clarithromycin to eradicate H. pylori, use clarithromycin and amoxicillin in combination with omeprazole in patients with a 1-yr history of duodenal ulcers or active duodenal ulcers to eradicate H. pylori ; short-term treatment of active benign gastric ulcer.

Posterior laryngitis; enhanced efficacy of pancreatin for treatment of steatorrhea in cystic fibrosis.

What is Generic Prilosec (Omeprazole)

Generic Prilosec belong to calss GI. Generic Prilosec Suppresses gastric acid secretion by blocking “acid (proton) pump” within gastric parietal cell.

Generic Prilosec (Omeprazole) Dosage or Administration

Active Duodenal Ulcer

Adults: PO 20 mg/day for 4 to 8 wk.

Erosive Esophagitis

Adults: PO 20 mg/day for 4 to 8 wk. Maintenance: 20 mg/day.

Pathologic Hypersecretory Conditions

Adults: PO Initial dose: 60 mg/day. Doses up to 120 mg tid have been given. Divide daily doses more then 80 mg.

H. pylori

Adults (triple therapy): PO 20 mg omeprazole plus clarithromycin 500 mg plus amoxicillin 1000 mg each given bid for 10 days; continue omeprazole 20 mg/day for an additional 18 days if an ulcer is present at start of therapy. Adults (dual therapy): PO 40 mg omeprazole once daily plus clarithromycin 500 mg tid for 14 days; continue omeprazole 20 mg/day for an additional 14 days if an ulcer is present at start of therapy.

Gastric ulcer

Adults: PO 40 mg once daily for 4 to 8 wk.

GERD

Adults (without esophageal lesions): PO 20 mg/day for 4 wk. Adults (with erosive esophagitis): PO 20 mg/day for 4 to 8 wk.

Precautions for Taking Generic Prilosec (Omeprazole)

Pregnancy: Category C. Lactation: Undetermined. Children: Safety and efficacy in children not established.

Interaction of Generic Prilosec (Omeprazole) with Other Drugs

Benzodiazepines: Clearance of benzodiazepines may be decreased. Cilostazol: Plasma levels may be increased by omeprazole, increasing the therapeutic and adverse effects. Clarithromycin: Serum concentrations of clarithromycin and omeprazole may be increased. Drugs depending on gastric pH for bioavailability (eg, ketoconazole, iron salts, ampicillin): Absorption of these drugs may be affected. Phenytoin: Decreased plasma clearance and increased phenytoin half-life. Warfarin: Prolonged warfarin elimination.

Side effects of Generic Prilosec (Omeprazole)

CARDIOVASCULAR: Angina; tachycardia; bradycardia; palpitation. CNS: Headache; dizziness. DERMATOLOGIC: Rash. GI: Diarrhea; abdominal pain; acid regurgitation; nausea; vomiting; constipation; flatulence. RESPIRATORY: Cough; upper respiratory tract infection. OTHER: Asthenia; back pain.
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