Information About Generic Plendil (Felodipine)

What is Generic Plendil (Felodipine)

Working of Generic Plendil (Felodipine)

Generic Plendil (Felodipine) Dosage or Administration

Precautions for Taking Generic Plendil (Felodipine)

Interaction of Generic Plendil (Felodipine) with Other Drugs

Side effects of Generic Plendil (Felodipine)

Felodipine is generic equivalent of Plendil, it is used for Treatment of hypertension.

What is Generic Plendil (Felodipine)

Generic Plendil belong to calss Calcium channel blocker. Generic Plendil Inhibits movement of calcium ions across cell membrane in systemic and coronary vascular smooth muscle, altering contractile process.

Generic Plendil (Felodipine) Dosage or Administration

PO 2.5 to 10 mg once daily. Maximum 20 mg once daily. Elderly rarely require > 10 mg qd.

Precautions for Taking Generic Plendil (Felodipine)

Pregnancy: Category C. Lactation: Undetermined. Children: Safety and efficacy not established. Elderly patients: May have greater hypotensive effects and increased risk of peripheral edema when dosage exceeds 20 mg/day. Monitor closely; doses > 10 mg usually not needed. CHF: Use with caution. Hepatic impairment: Use with caution in patients with impaired hepatic function or reduced hepatic blood flow. Withdrawal syndrome: Abrupt withdrawal may cause increased frequency and duration of angina. Taper dose gradually.

Interaction of Generic Plendil (Felodipine) with Other Drugs

Barbiturates: Effects of felodipine may be decreased. Carbamazepine: Plasma levels of felodipine may be decreased, reducing effect. Food: Effects of felodipine may increase if given with grapefruit juice. Histamine H2 antagonists: Cimetidine may increase effects of felodipine. Hydantoins: Serum felodipine levels may be decreased, reducing effects. Other antihypertensive agents: May have additive effects.

Side effects of Generic Plendil (Felodipine)

CV: Peripheral edema; hypotension; syncope; AV block; MI; arrhythmias; angina; tachycardia. CNS: Headache; dizziness; lightheadedness; nervousness; psychiatric disturbances; paresthesias; somnolence; asthenia; insomnia; anxiety; irritability. GI: Nausea; diarrhea; constipation; abdominal discomfort; cramps; dyspepsia; vomiting; dry mouth; thirst; flatulence. GU: Micturition disorders; sexual difficulties. HEMA: Epistaxis. RESP: Nasal or chest congestion; sinusitis; rhinitis; pharyngitis; shortness of breath; wheezing; cough; sneezing; respiratory infections. OTHER: Muscle cramps, pain, or inflammation; gingival hyperplasia.