Information About Generic Luvox (Fluvoxamine)

What is Generic Luvox (Fluvoxamine)

Working of Generic Luvox (Fluvoxamine)

Generic Luvox (Fluvoxamine) Dosage or Administration

Precautions for Taking Generic Luvox (Fluvoxamine)

Interaction of Generic Luvox (Fluvoxamine) with Other Drugs

Side effects of Generic Luvox (Fluvoxamine)

Fluvoxamine is generic equivalent of Luvox, it is used for Treatment of obsessive-compulsive disorder as defined in DSM-III-R.

What is Generic Luvox (Fluvoxamine)

Generic Luvox belong to calss Antidepressant, Selective serotonin inhibitor. Generic Fluvoxamine Inhibits neuronal reuptake of serotonin in brain.

Generic Luvox (Fluvoxamine) Dosage or Administration

ADULTS: PO 50 mg as a single dose at bedtime initially. Usual range: 100 to 300 mg/day. Increase dose in 50 mg increments q 4 to 7 days, as tolerated, until max therapeutic benefit is achieved (max 300 mg/day). Give total daily doses > 100 mg in 2 divided doses; if doses are unequal, give larger dose at bedtime. Maintenance: Dosage is adjusted to maintain patient on lowest effective dosage. Periodically reassess need to continue treatment.

Precautions for Taking Generic Luvox (Fluvoxamine)

Pregnancy: Category C. Lactation: Excreted in breast milk. Children: Safety and efficacy in patients < 18 yr have not been established. Elderly/Hepatically Impaired Patients: Because of decreased drug clearance, reduce initial dose and titrate slowly. Cognitive and Motor Performance: Patients should use caution in operating potentially hazardous machinery (eg, driving) until they know whether the drug impairs their ability. Use of alcohol also should be avoided. Concomitant Illness: Caution is advised in using drug in patients with diseases or conditions that could affect hemodynamic responses or metabolism (eg, liver dysfunction). Mania/Hypomania: Fluvoxamine may activate hypomania or mania. Use cautiously in patients with history of mania. Seizures: Use with caution in patients with history of seizures. Seizures have been reported in small numbers of patients given this drug.

Interaction of Generic Luvox (Fluvoxamine) with Other Drugs

Lithium, Tryptophan: May enhance serotonergic effects of fluvoxamine.

MAOIs: Similar selective serotonin inhibitors can cause serious (sometimes fatal) reactions. Do not give fluvoxamine in combination with MAOI or < 14 days of discontinuation of MAOI. After stopping fluvoxamine, wait ³ 2 wk before starting MAOI.

Smoking: Increases metabolism of fluvoxamine.

Warfarin, Clozapine, Tricyclic Antidepressants, Benzodiapines (eg, alprazolam, diazapam, midazolam, triazolam), Carbamazepine, Methadone, Metoprolol, Propranolol: Plasma levels of these drugs may be increased.

Cisapride: Increased plasma concentrations of cisapride cause QT prolongation and have been associated with torsades de pointes-type ventricular tachycardia, sometimes fatal.

Side effects of Generic Luvox (Fluvoxamine)

CARDIOVASCULAR: Palpitations; vasodilation. RESPIRATORY: Upper respiratory infection; dyspnea; yawning. CNS: Headache; somnolence; insomnia; nervousness; dizziness; tremor; anxiety; hypertonia; agitation; decreased libido; depression; stimulation. EENT: Taste perversion; amblyopia. GI: Nausea; vomiting; diarrhea; constipation; dyspepsia; anorexia; flatulence; tooth disorders (eg, toothache, caries); dysphagia; dry mouth. GU: Abnormal ejaculation; urinary frequency; impotence; anorgasmia; urinary retention. DERMATOLOGIC: Sweating; rash; hives. OTHER: Asthenia; flu syndrome; chills.
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