Information About Generic Lasix (Furosemide)

What is Generic Lasix (Furosemide)

Working of Generic Lasix (Furosemide)

Generic Lasix (Furosemide) Dosage or Administration

Precautions for Taking Generic Lasix (Furosemide)

Interaction of Generic Lasix (Furosemide) with Other Drugs

Side effects of Generic Lasix (Furosemide)

Furosemide is generic equivalent of Lasix, it is used for Treatment of edema associated with CHF, hepatic cirrhosis, and renal disease; hypertension.

What is Generic Lasix (Furosemide)

Generic Lasix belong to calss Loop diuretic. Generic Lasix Inhibits reabsorption of sodium and chloride in proximal and distal tubules and loop of Henle.

Generic Lasix (Furosemide) Dosage or Administration

Edema

ADULTS: PO 20 to 80 mg/day as a single dose; may titrate up to 600 mg/day. IV/IM 20 to 40 mg qd or bid.

Hypertension

ADULTS: PO 40 mg bid. Maximum dose: 6 mg/kg.

CHF and Chronic Renal Failure

ADULTS: PO Up to 2 to 2.5 g/day. IV Up to 2 to 2.5 g/day. Maximum IV bolus: 1 g/day over 30 min.

Precautions for Taking Generic Lasix (Furosemide)

Pregnancy: Category C. Lactation: Excreted in breast milk. Children: May increase incidence of patent ductus arteriosus in premature infants with respiratory distress syndrome, especially in first few weeks of life. Dehydration: Excessive diuresis may cause dehydration and decreased blood volume with circulatory collapse and possible vascular thrombosis and embolism, especially in elderly. Diarrhea: Furosemide solution vehicle contains sorbitol and may induce diarrhea, especially in children. Hepatic cirrhosis and ascites: Sudden alterations of electrolyte balance may precipitate hepatic encephalopathy and coma; monitor carefully. Hypersensitivity: Patients with known sulfonamide sensitivity may show allergic reactions to furosemide. Ototoxicity: Associated with rapid injection, severe renal impairment, very large doses, or concurrent use of other ototoxic drugs. Photosensitivity: Photosensitization may occur. Renal impairment: If severe effects occur, may need to discontinue. If high-dose parenteral therapy is used, controlled IV infusion is advised. Systemic lupus erythematosus: May be exacerbated or activated.

Interaction of Generic Lasix (Furosemide) with Other Drugs

Aminoglycosides: May increase auditory toxicity. Charcoal: May reduce absorption of furosemide. Cisplatin: May cause additive ototoxicity. Digitalis glycosides: Electrolyte disturbances may predispose to digitalis-induced arrhythmias. Lithium: May increase plasma lithium levels and toxicity. Nonsteroidal anti-inflammatory drugs: May decrease effects of furosemide. Phenytoin: May reduce diuretic effects of furosemide. Salicylates: May impair diuretic response in patients with cirrhosis and ascites. Thiazide diuretics: Synergistic effects that may result in profound diuresis and serious electrolyte abnormalities. INCOMPATIBILITIES: Gentamicin, milrinone, or netilmicin in D5W or normal saline: Do not add to furosemide solution; precipitate forms. Highly acidic solutions of pH < 5.5: Do not mix with furosemide solution.

Side effects of Generic Lasix (Furosemide)

CV: Orthostatic hypotension; thrombophlebitis; chronic aortitis. CNS: Vertigo; headache; dizziness; paresthesia; restlessness; fever. DERM: Photosensitivity; urticaria; pruritus; necrotizing angiitis (eg, vasculitis, cutaneous vasculitis); exfoliative dermatitis; erythema multiforme; rash; occasionally, local irritation and pain with parenteral use. EENT: Blurred vision; xanthopsia (yellow vision); tinnitus; hearing impairment. GI: Anorexia; nausea; vomiting; diarrhea; oral and gastric irritation; cramping; constipation; pancreatitis. GU: Urinary bladder spasm; interstitial nephritis; glycosuria. HEMA: Anemia; leukopenia; purpura; aplastic anemia; thrombocytopenia; agranulocytosis. HEPA: Jaundice; ischemic hepatitis. META: Hyperuricemia; hyperglycemia; hypokalemia; metabolic alkalosis. OTHER: Muscle spasm; weakness.