Information About Generic Ilosone (Erythromycin)

What is Generic Ilosone (Erythromycin)

Working of Generic Ilosone (Erythromycin)

Generic Ilosone (Erythromycin) Dosage or Administration

Precautions for Taking Generic Ilosone (Erythromycin)

Interaction of Generic Ilosone (Erythromycin) with Other Drugs

Side effects of Generic Ilosone (Erythromycin)

Erythromycin is generic equivalent of Ilosone, it is used for Oral/intravenous use: Treatment of infections of respiratory tract, skin and skin structure, and sexually transmitted diseases due to susceptible organisms; treatment of pertussis, diphtheria, erythrasma, intestinal amebiasis, conjunctivitis of newborn and Legionnaire's disease; prevention of attacks of rheumatic fever; prevention of bacterial endocarditis; treatment of acute otitis media (in combination with sulfisoxazole). Ophthalmic use: Treatment of superficial ocular infections due to strains of susceptible organism. Topical use: Infection prophylaxis in minor cuts, wounds, burns and skin abrasions; treatment of acne vulgaris. Unlabeled use(s): Treatment of Neisseria gonorrhoeae in pregnancy; treatment of diarrhea caused by Campylobacter jejuni; as alternative to penicillin in selected infections.

What is Generic Ilosone (Erythromycin)

Generic Ilosone belong to calss Antibiotic/macrolide. Generic Ilosone Interferes with microbial protein synthesis.

Generic Ilosone (Erythromycin) Dosage or Administration

Systemic Use

ADULTS: PO 250–500 mg of base (400–800 mg ethylsuccinate) q 6 hr or 500 mg q 12 hr or 333 mg q 8 hr. IV 15–20 mg/kg/day; up to 4 g/day in very severe infections. CHILDREN: PO 30 to 50 mg/kg/day in divided doses.

Acute Ocular Infection

ADULTS & CHILDREN: Ophthalmic 0.5 inch ribbon of ointment placed in eye q 3–4 hr.

Mild to Moderate Ocular Infection

ADULTS & CHILDREN: Ophthalmic 0.5 inch ribbon of ointment placed in eye bid-tid.

Prophylaxis of Neonatal Gonococcal or Chlamydia Conjunctivitis

NEONATES: Ophthalmic 0.2–0.4 inch ribbon of ointment placed in each conjunctival sac at time of delivery.

Skin Infections

ADULTS & CHILDREN: Topical Apply 1–4 times daily to affected area.

Acne Vulgaris

ADULTS & CHILDREN: Topical Apply bid.

Precautions for Taking Generic Ilosone (Erythromycin)

Pregnancy: Category B. Lactation: Excreted in breast milk. Acne therapy: Cumulative irritant effect may occur. Hepatic impairment: Use drug cautiously. Hepatic dysfunction, with or without jaundice, has occurred. Cholestatic hepatitis has occurred. Hypersensitivity: Serious reactions, including anaphylaxis, have occurred. Ophthalmic ointments: May slow corneal epithelial healing. Ototoxicity: May occur, especially in patients with renal or hepatic insufficiency and elderly patients and with administration of large doses. Pseudomembranous colitis: Consider possibility in patients in whom diarrhea develops. Superinfection: Prolonged use of antibiotics may result in bacterial or fungal overgrowth of nonsusceptible microorganisms.

Interaction of Generic Ilosone (Erythromycin) with Other Drugs

Anticoagulants: May increase anticoagulant effects. Antihistamines, non-sedating (eg, astemizole, terfenadine): May increase antihistamine levels and cause serious adverse cardiovascular events, including ventricular arrhythmias and death. Bromocriptine: May increase serum bromocriptine levels. Carbamazepine: May result in serious carbamazepine toxicity. Clindamycin, topical: Antagonism may occur with topical erythromycin. Cyclosporine: May cause increased cyclosporine levels with renal toxicity. Digoxin: May cause increased digoxin levels. Lovastatin: Severe myopathy or rhabdomyolysis may occur. Methylprednisolone: May decrease clearance of methylprednisolone. Theophyllines: May increase theophylline plasma concentration.

Side effects of Generic Ilosone (Erythromycin)

DERM: Rash; photosensitivity; erythema and peeling (topical use). GI: Diarrhea; nausea; vomiting abdominal pain/cramping. GU: Vaginitis. HEPA: Hepatotoxicity (primarily with estolate salt). OTHER: Venous irritation or phlebitis with IV administration.