Information About Generic Feldene (Piroxicam)

What is Generic Feldene (Piroxicam)

Working of Generic Feldene (Piroxicam)

Generic Feldene (Piroxicam) Dosage or Administration

Precautions for Taking Generic Feldene (Piroxicam)

Interaction of Generic Feldene (Piroxicam) with Other Drugs

Side effects of Generic Feldene (Piroxicam)

Piroxicam is generic equivalent of Feldene, it is used for Treatment of acute or long-term use of rheumatoid arthritis and osteoarthritis. Unlabeled use(s): Symptomatic relief of primary dysmenorrhea, pain, sunburn, juvenile rheumatoid arthritis.

What is Generic Feldene (Piroxicam)

Generic Feldene belong to calss Analgesic/NSAID. Generic Feldene Decreases inflammation, pain and fever, probably through inhibition of cyclooxygenase activity and prostaglandin synthesis.

Generic Feldene (Piroxicam) Dosage or Administration

Rheumatoid Arthritis, Osteoarthritis

ADULTS: PO Initiate and maintain at 20 mg/day in 1 to 2 divided doses.

Precautions for Taking Generic Feldene (Piroxicam)

Pregnancy: Category C. Lactation: Undetermined. Children: Safety and efficacy not established. Elderly: Increased risk of adverse reactions. May require decreased dosage. Asthma: In certain patients (aspirin-allergic, nasal polyps) may precipitate asthma attacks. Cardiovascular disease: May worsen CHF and hypertension. Coagulation disorders: Increases risk of bleeding. Dermatologic effects: Combination of dermatologic/allergic signs and symptoms (ie, arthralgias, pruritus, fever, fatigue, rash including vesiculobullous reactions, exfoliative dermatitis) suggestive of serum sickness have occurred. GI effects: Serious GI toxicity can occur at any time, with or without warning symptoms. Renal disease: Drug may accumulate, increasing the risk of toxicity. In cases of advanced kidney disease, treatment with piroxicam is not recommended.

Interaction of Generic Feldene (Piroxicam) with Other Drugs

Alcohol: May augment risk of GI bleeding. Anticoagulants: May increase effect of anticoagulants due to decreased plasma protein binding and inhibition of platelet aggregation. May increase risk of gastric erosion and bleeding. Beta-blockers: Antihypertensive effect may be decreased. Cholestyramine: Effects of piroxicam may be decreased. Lithium: May decrease lithium clearance. Methotrexate: May increase methotrexate levels and methotrexate toxicity. Ritonivir: May increase concentrations and possibly the toxicity of piroxicam by inhibiting its metabolism.

Side effects of Generic Feldene (Piroxicam)

CV: Edema; weight gain; CHF; alterations in BP; vasodilation; palpitations; tachycardia. CNS: Headache; malaise; dizziness; somnolence; vertigo; depression; insomnia; nervousness. DERM: Pruritus; rash; sweating; erythema; bruising; desquamation; erythema multiforme; toxic epidermal necrolysis. EENT: Tinnitus; swollen eyes; blurred vision; eye irritation; rhinitis; pharyngitis. GI: Epigastric distress; nausea; vomiting; anorexia; constipation; stomatitis; abdominal discomfort; diarrhea; flatulence; abdominal pain; indigestion; toxicity (bleeding, ulceration, perforation); heartburn; dyspepsia; anorexia. GU: Hematuria; proteinuria; increased BUN and serum creatinine; acute renal insufficiency and failure; papillary necrosis; interstitial nephritis; nephrotic syndrome; hyperkalemia; hyponatremia. HEMA: Increased bleeding time; decreased Hgb and Hct; anemia; leukopenia; eosinophilia, thrombocytopenia. HEPA: Increased liver function tests; elevated liver enzymes. RESP: Bronchospasm; laryngeal edema; dyspnea; hemoptysis; shortness of breath.
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