Information About Generic Effexor (Venlafaxine)

What is Generic Effexor (Venlafaxine)

Working of Generic Effexor (Venlafaxine)

Generic Effexor (Venlafaxine) Dosage or Administration

Precautions for Taking Generic Effexor (Venlafaxine)

Interaction of Generic Effexor (Venlafaxine) with Other Drugs

Side effects of Generic Effexor (Venlafaxine)

Venlafaxine is generic equivalent of Effexor, it is used for Treatment of depression; generalized anxiety disorder (venlafaxine ER).

What is Generic Effexor (Venlafaxine)

Generic Effexor belong to calss Antidepressant. Generic Effexor Potentiates norepinephrine, serotonin, and dopamine neurotransmitter activity in CNS.

Generic Effexor (Venlafaxine) Dosage or Administration

Depression

ADULTS (immediate-release): PO 75 mg/day in 2 or 3 divided doses; titrate to clinical effect, adding up to 75 mg/day at intervals of ³ 4 days (max, 375 mg/day).

ADULTS (extended-release): PO 75 mg/day administered in single dose either in morning or evening at approximately same time each day. Make dose increases in increments of up to 75 mg/day as needed and at intervals of ³ 4 days.

Generalized Anxiety Disorder

ADULTS (extended-release): PO The usual dosage is 75 to 225 mg/day. Some patients may need to start with 37.5 mg/day to avoid overstimulation.

Precautions for Taking Generic Effexor (Venlafaxine)

Pregnancy: Category C. Lactation: Excreted in breast milk. CHILDREN: Safety and efficacy in patients < 18 yr not established. Elderly: Take extra care when increasing dose in elderly patients. Special Risk Patients: Use drug with caution in patients with history of seizure, mania, suicidal tendencies, drug abuse, or dependence. Hepatic or Renal Impairment: Reduction of dose may be necessary. Use drug with caution. Hypertension: Regular monitoring of BP is recommended. Venlafaxine is associated with sustained but small increases in BP (usually associated with doses > 300 mg/day). Discontinuation: After 1 wk of therapy, dosage requires tapering if discontinuing; after 6 wk of treatment, taper over 2-wk period.

Interaction of Generic Effexor (Venlafaxine) with Other Drugs

Desipramine, Haloperidol: Plasma levels of these drugs may be elevated by venlavaxine, increasing the risk of adverse effects. MAOIs: MAOIs have produced serious, even fatal, reactions when given concomitantly with venlafaxine. Do not use venlafaxine together with MAOIs or within 14 days of MAOI use. Wait ³ 7 days after stopping venlafaxine before using MAOI. St. John’s Wort: Increased sedative-hypnotic effects may occur. Sibutramine, Sumatriptan, Trazodone: A “serotinin syndrome,” including irritability, increased muscle tone, shivering, myoclonus, and altered consciousness may occur.

Side effects of Generic Effexor (Venlafaxine)

CARDIOVASCULAR: Hypertension; migraine; vasodilation; tachycardia; postural hypotension. CNS: Insomnia; somnolence; anxiety; headache; dizziness; nervousness; tremor; asthenia; abnormal dreams; hypertonia; paresthesia; agitation; confusion; abnormal thinking; depersonalization; twitching. DERMATOLOGIC: Sweating; rash; pruritus. EENT: Blurred vision; taste perversion; tinnitus; mydriasis. GI: Nausea; anorexia; dry mouth; constipation; dysphagia; diarrhea; vomiting; dyspepsia; flatulence; weight loss. GU: Abnormal ejaculation or orgasm; dysuria; hematuria; increased BUN; vaginitis; decreased libido; urinary retention; impotence; urinary frequency; anorgasmia (female); impaired urination; orgasm disturbance; menstrual disorder. HEMATOLOGIC: Ecchymosis. HEPATIC: Increased LFT results and bilirubin. METABOLIC: Peripheral edema; weight gain. RESPIRATORY: Dyspnea. OTHER: Pharyngitis; infection; chills; chest pain; trauma; yawn.
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