Information About Generic Ceftin (Cefuroxime)

What is Generic Ceftin (Cefuroxime)

Working of Generic Ceftin (Cefuroxime)

Generic Ceftin (Cefuroxime) Dosage or Administration

Precautions for Taking Generic Ceftin (Cefuroxime)

Interaction of Generic Ceftin (Cefuroxime) with Other Drugs

Side effects of Generic Ceftin (Cefuroxime)

Cefuroxime is generic equivalent of Ceftin, it is used for Treatment of infections of lower respiratory tract, urinary tract, skin and skin structures; treatment of uncomplicated gonorrhea, otitis media, pharyngitis and tonsillitis due to susceptible strains of specific micro-organisms. Treatment of early Lyme disease, pharyngitis/tonsillitis and impetigo. Parenteral form: Treatment of infections of lower respiratory tract, urinary tract, skin and skin structures, bone and joint; preoperative prophylaxis; treatment of septicemia, gonorrhea and meningitis due to susceptible strains of specific microorganisms.

What is Generic Ceftin (Cefuroxime)

Generic Ceftin belong to calss Antibiotic/cephalosporin. Generic Ceftin Inhibits mucopeptide synthesis in bacterial cell wall.

Generic Ceftin (Cefuroxime) Dosage or Administration

Infection

ADULTS & CHILDREN ³ 12 YR: PO 125–500 mg bid. IV/IM 750 mg-1.5 g q 8 hr. CHILDREN < 12 YR: PO 125–250 mg bid. Infants & CHILDREN (> 3 MO): IV/IM 50–150 mg/kg/day (not to exceed adult dose) in equally divided doses q 6–8 hr.

Bacterial Meningitis

ADULTS & CHILDREN ³ 12 YR: IV/IM Up to 3 g q 8 hr. INFANTS & CHILDREN 3 MO-12 YR: IV/IM 200–240 mg/kg/day in divided doses q 6–8 hr.

Uncomplicated Gonorrhea

ADULTS & CHILDREN ³ 12 YR: PO 1 g as single dose. IM 1.5 g as single dose.

Preoperative Prophylaxis

ADULTS: IV/IM 1.5 g ½–1 hr before surgery then 750 mg q 8 hr for duration of surgery.

Precautions for Taking Generic Ceftin (Cefuroxime)

Pregnancy: Category B. Lactation: Excreted in breast milk. Children: Safety and efficacy in children < 3 mo not established. Hypersensitivity: Reactions range from mild to life-threatening. Administer drug with caution to penicillin-sensitive patients due to possible cross-reactivity. Pseudomembranous colitis: Should be considered in patients in whom diarrhea develops. Renal impairment: Use drug with caution in patients with renal impairment. Dosage adjustment based on renal function may be required. Superinfection: May result in bacterial or fungal overgrowth of non-susceptible microorganisms.

Interaction of Generic Ceftin (Cefuroxime) with Other Drugs

Aminoglycosides: Increased risk of nephrotoxicity with parenteral cefuroxime. Probenecid: Inhibition of renal excretion of cefuroxime. INCOMPATIBILITIES: Aminoglycosides: Do not add aminoglycosides to cefuroxime solutions because inactivation of both drugs may result; administer at separate sites if concurrent therapy is indicated.

Side effects of Generic Ceftin (Cefuroxime)

GI: Nausea; vomiting; diarrhea; anorexia; abdominal pain or cramps; flatulence; colitis, including pseudomembranous colitis. GU: Pyuria; renal dysfunction; dysuria; reversible interstitial nephritis; hematuria; toxic nephropathy. HEMA: Eosinophilia; neutropenia; lymphocytosis; leukocytosis; thrombocytopenia; decreased platelet function; anemia; aplastic anemia; hemorrhage. HEPA: Hepatic dysfunction; abnormal liver function test results. OTHER: Hypersensitivity, including Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis; candidal overgrowth; serum sickness-like reactions (eg, skin rashes, polyarthritis, arthralgia, fever); phlebitis, thrombophlebitis and pain at injection site.
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