Information About Generic Cardizem (Diltiazem)

What is Generic Cardizem (Diltiazem)

Working of Generic Cardizem (Diltiazem)

Generic Cardizem (Diltiazem) Dosage or Administration

Precautions for Taking Generic Cardizem (Diltiazem)

Interaction of Generic Cardizem (Diltiazem) with Other Drugs

Side effects of Generic Cardizem (Diltiazem)

Diltiazem is generic equivalent of Cardizem, it is used for Treatment of angina pectoris caused by coronary artery spasm; chronic stable angina (classic effort-associated angina); essential hypertension (extended- and sustained-release forms only). Parenteral: Treatment of atrial fibrillation or flutter; paroxysmal supraventricular tachycardia.

What is Generic Cardizem (Diltiazem)

Generic Cardizem belong to calss Calcium channel blocker. Generic Cardizem Inhibits movement of calcium ions across cell membrane in systemic and coronary vascular smooth muscle; slows calcium ion movement across cell membranes in both cardiac muscle and cardiac pacemaker cells, decreasing sinoatrial and atrioventricular (AV) conduction.

Generic Cardizem (Diltiazem) Dosage or Administration

Precautions for Taking Generic Cardizem (Diltiazem)

Pregnancy: Category C. Lactation: Excreted in breast milk. CHILDREN: Safety and efficacy not established. CHF: Use with caution. Hepatic or renal impairment: Use with caution. Dosage may need to be decreased. Withdrawal syndrome: Abrupt withdrawal may cause increased frequency and duration of angina. Dosage is tapered gradually.

Interaction of Generic Cardizem (Diltiazem) with Other Drugs

Beta-blockers: May have additive negative inotropic and chronotropic effects. Carbamazepine: Carbamazepine levels may increase. Cimetidine, ranitidine: Diltiazem levels may be increased. Cyclosporine: Cyclosporine levels and toxicity may increase. Encainide: Encainide levels may increase. Other antihypertensive agents: May have additive effects.

Do not mix with furosemide.

Side effects of Generic Cardizem (Diltiazem)

CARDIOVASCULAR: Peripheral edema; hypotension (especially during initial treatment or with dose increases); bradycardia; angina; AV block; abnormal ECG; arrhythmias. CNS: Dizziness, lightheadedness; headache; weakness; shakiness; somnolence; asthenia. DERMATOLOGIC: Dermatitis; photosensitivity; petechiae; rash; hair loss; erythema multiforme; Stevens-Johnson syndrome. GI: Nausea; vomiting; constipation; abdominal discomfort; cramps; dyspepsia; dry mouth. HEMATOLOGIC: Leukopenia. OTHER: Flushing; micturation disorder; gingival hyperplasia; gynecomastia; joint pain.
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