Information About Generic Carbatrol (Carbamazepine)

What is Generic Carbatrol (Carbamazepine)

Working of Generic Carbatrol (Carbamazepine)

Generic Carbatrol (Carbamazepine) Dosage or Administration

Precautions for Taking Generic Carbatrol (Carbamazepine)

Interaction of Generic Carbatrol (Carbamazepine) with Other Drugs

Side effects of Generic Carbatrol (Carbamazepine)

Carbamazepine is generic equivalent of Carbatrol, it is used for Treatment of epilepsy (partial seizures with complex symptoms, generalized tonic-clonic seizures [grand mal], mixed seizure patterns or other partial or generalized seizures), in patients refractory to or intolerant of other agents. Treatment of pain of trigeminal neuralgia. Unlabeled use(s): Management of neurogenic diabetes insipidus; treatment of certain psychiatric disorders; management of alcohol, cocaine and benzodiazepine withdrawal; relief of restless legs syndrome. Nonhereditary chorea in children.

What is Generic Carbatrol (Carbamazepine)

Generic Carbatrol belong to calss Anticonvulsant. Generic Carbatrol Mechanism appears to act by reducing polysynaptic responses and blocks post-tetanic potentiation.

Generic Carbatrol (Carbamazepine) Dosage or Administration

ADULTS: Initial dose: PO 200 mg bid (tablets) or 100 mg qid (suspension).

Precautions for Taking Generic Carbatrol (Carbamazepine)

Pregnancy: Category D. Lactation: Excreted in breast milk. Children: Safety and efficacy in children < 6 yr not established. Elderly: May make elderly more prone to CNS side effects; may cause confusion, agitation or activation of latent psychosis. Special-risk patients: Use with caution in patients with prior adverse hematologic reactions to any drug; glaucoma; cardiac, hepatic or renal disease; and mixed seizure disorders, including absence seizures. Aplastic anemia and agranulocytosis: Has been associated with carbamazepine therapy. The risk of developing these reactions is 5 to 8 times greater than in the general population; however, the overall risk of these reactions in the untreated general population is low. Obtain complete pretreatment hematological testing as a baseline. If in the course of treatment, a patient exhibits low are decreased white blood cell or platelet counts, monitor the patient closely.

Interaction of Generic Carbatrol (Carbamazepine) with Other Drugs

Anticoagulants: May decrease anticoagulant effects. Barbiturates: May result in decreased carbamazepine serum concentrations, possibly leading to decreased effectiveness. Charcoal, activated: May reduce absorption of carbamazepine. Cimetidine: May result in carbamazepine toxicity. Contraceptives, oral: Causes breakthrough bleeding and reduces effectiveness of contraceptives. Diltiazem, verapamil, danazol, propoxyphene, macrolide antibiotics (except azithromycin): May increase carbamazepine levels and may result in toxicity. Doxycycline hyclate: May decrease doxycycline hyclate levels. Felbamate: May decrease concentrations of felbamate or carbamazepine. Felodipine: May decrease effects of felodipine. Haloperidol: May decrease effects of haloperidol. Hydantoins (eg, phenytoin): May decrease carbamazepine levels; may alter hydantoin levels. Isoniazid: May result in toxicity of isoniazid, carbamazepine or both. Lithium: May cause adverse CNS effects regardless of drug levels. Macrolide antibiotics (eg, clarithromycin, erythromycin, troleandomycin): May increase toxicity. Nondepolarizing muscle relaxants: May make these agents less effective. Primidone: Decreased carbamazepine levels. Primidone's active metabolite (phenobarbital) may be increased. Propoxyphene: Increases carbamazepine levels. SSRIs (fluoxetine, fluvoxamine): Increased carbamazepine levels with possible toxicity. Theophylline: May reduce effects of theophylline and carbamazepine. Theophylline levels may be increased or decreased. Tricyclic antidepressants: May increase carbamazepine levels; may decrease tricyclic antidepressant levels. Valproic acid: May decrease valproic acid levels; may alter carbamazepine levels. Verapamil: Concomitant therapy has resulted in symptoms of toxicity.

Side effects of Generic Carbatrol (Carbamazepine)

CV: AV block; CHF; hypertension; hypotension; syncope; edema; thrombophlebitis; aggravation of coronary artery disease; arrhythmias. CNS: Dizziness; drowsiness; unsteadiness; confusion; headache; hyperacusis; fatigue; speech disturbances; abnormal involuntary movements; peripheral neuritis and paresthesias; depression with agitation; talkativeness; behavior changes (children); paralysis. DERM: Pruritic and erythematous rashes; exfoliative dermatitis; erythema multiforme and nodosum; purpura; aggravation of disseminated lupus erythematosus; toxic epidermal necrolysis; urticaria; photosensitivity; pigment changes; alopecia; diaphoresis; Stevens-Johnson syndrome. EENT: Blurred vision; visual hallucinations; diplopia; nystagmus; punctate cortical lens opacities; conjunctivitis; tinnitus; dryness and irritation of the mouth and throat. GI: Nausea; vomiting; gastric distress; abdominal pain; diarrhea; constipation; anorexia
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