Information About Generic Brethaire (Terbutaline)

What is Generic Brethaire (Terbutaline)

Working of Generic Brethaire (Terbutaline)

Generic Brethaire (Terbutaline) Dosage or Administration

Precautions for Taking Generic Brethaire (Terbutaline)

Interaction of Generic Brethaire (Terbutaline) with Other Drugs

Side effects of Generic Brethaire (Terbutaline)

Terbutaline is generic equivalent of Brethaire, it is used for Treatment of reversible bronchospasm associated with asthma, bronchitis and emphysema. unlabeled use (S): Inhibits premature labor.

What is Generic Brethaire (Terbutaline)

Generic Brethaire belong to calss Bronchodilator. Generic Brethaire Produces bronchodilation by relaxing bronchial smooth muscle through beta2-receptor stimulation.

Generic Brethaire (Terbutaline) Dosage or Administration

ADULTS & CHILDREN ³ 12 YR: Inhalation 2 inhalations (separated by 60 sec interval) q 4–6 hr. Do not repeat more than q 4 hr. ADULTS & CHILDREN ³ 15 YR: PO 2.5–5 mg at 6 hr intervals, 3 times per day during waking hours. Do not exceed 15 mg in 24 hr. CHILDREN 12–15 YR: PO 2.5 mg tid. Do not exceed 7.5 mg in 24 hr. SC 0.25 mg given in lateral deltoid area. May repeat in 15–30 min. Do not exceed 0.5 mg in 4 hr.

Premature Labor Inhibition

ADULTS: IV 10–80 mcg/min for 4 hr has shown some success. Maintenance: PO 2.5 mg q 4–6 hr.

Precautions for Taking Generic Brethaire (Terbutaline)

Pregnancy: Category B. Lactation: Excreted in breast milk. Labor and delivery: May inhibit uterine contractions and delay preterm labor. Children: Safety and efficacy in children < 12 years not established. Elderly: Lower doses may be required. Cardiovascular effects: Toxic symptoms in patients with cardiovascular disorders may occur. CNS effects: CNS stimulation may occur; use cautiously in patients with history of seizures or hyperthyroidism. Carcinogenesis: A significant increase in the incidence of leiomyomas of the mesovarium and ovarian cysts has been demonstrated. Diabetes: Dosage adjustment of insulin or oral hypoglycemic agent may be required. Excessive use: Paradoxical bronchospasm and cardiac arrest have been associated with excessive inhalant use. Hypersensitivity: Hypersensitivity (allergic) reactions can occur after administration. Hypokalemia: Decreases in potassium levels have occurred. Tolerance: If previously effective dose fails to provide relief, therapy may need to be reassessed.

Interaction of Generic Brethaire (Terbutaline) with Other Drugs

Beta-blockers: Block bronchodilator effect of terbutaline. MAO inhibitors: Hypertension may occur. Tricyclic antidepressants: Cardiovascular effects of terbutaline may be enhanced.

Side effects of Generic Brethaire (Terbutaline)

CV: Palpitations; tachycardia; chest discomfort or pain; arrhythmias; blood pressure changes/hypertension. CNS: Stimulation; tremor; dizziness; nervousness; drowsiness; headache; weakness. GI: Nausea; vomiting; GI distress. HEPA: Elevated liver enzymes. META: Hypokalemia (with high doses). RESP: Dyspnea. OTHER: Flushing; sweating; muscle cramps; hypersensitivity vasculitis; ECG changes (eg, sinus pause, atrial premature beats, AV block, ventricular premature beats, ST-T-wave depression, T-wave inversion, sinus bradycardia, atrial escape beat with aberrant conduction); increased heart rate; muscle cramps; central stimulations; pain at injection site; elevations in liver enzymes; seizures; hypersensitivity vasculitis.
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