Information About Generic Betapace (Sotalol)

What is Generic Betapace (Sotalol)

Working of Generic Betapace (Sotalol)

Generic Betapace (Sotalol) Dosage or Administration

Precautions for Taking Generic Betapace (Sotalol)

Interaction of Generic Betapace (Sotalol) with Other Drugs

Side effects of Generic Betapace (Sotalol)

Sotalol is generic equivalent of Betapace, it is used for Management or prevention of life-threatening ventricular arrhythmias. Betapace AF: Maintenance of normal sinus rhythm in patients with highly symptomatic atrial fibrillation/atrial flutter (AFIB/AFL) (Betapace AF).

What is Generic Betapace (Sotalol)

Generic Betapace belong to calss Beta-adrenergic blocker. Generic Betapace Blocks beta receptors, which primarily affect heart (slows rate), vascular musculature (decreases blood pressure), and lungs (reduces function).

Generic Betapace (Sotalol) Dosage or Administration

Betapace should not be substituted for Betapace AF because of significant differences in labeling (eg, patient package insert, dosing administration and safety information). Betapace:

Ventricular Arrhythmias

ADULTS: PO 80 mg twice daily; may increase up to 320 mg/day in 2 or 3 divided doses.

Precautions for Taking Generic Betapace (Sotalol)

Pregnancy: Category B. Lactation: Excreted in breast milk. Children: Safety and efficacy not established. Abrupt withdrawal: Has been associated with adverse effects; gradually decrease dose over 1 to 2 wk. Anaphylaxis: Deaths have occurred; aggressive therapy may be required. CHF: Administer cautiously in patients with CHF controlled by digitalis and diuretics. Diabetic patients: Drug may mask signs and symptoms of hypoglycemia (eg, tachycardia, BP changes). Drug may potentiate insulin-induced hypoglycemia.

Interaction of Generic Betapace (Sotalol) with Other Drugs

Amiodarone, disopyramide, procainamide, quinidine: May prolong cardiac refractoriness. Calcium channel blockers: Increase risk of hypotension; possible increased effect on atrioventricular conduction or ventricular function. Clonidine: May enhance or reverse antihypertensive effects; may enhance clonidine rebound hypertension. Guanethidine, reserpine: Increase hypotension or bradycardia. Insulin, oral sulfonylurea hypoglycemic agents: Hyperglycemia; symptoms of hypoglycemia may be masked. NSAIDs: Some agents may impair antihypertensive effect.

Side effects of Generic Betapace (Sotalol)

CV: Arrhythmias; sustained ventricular tachycardia or fibrillation; torsades de pointes. CNS: Depression; dizziness; headache; lethargy; paresthesias; vivid dreams. DERM: Rash. GI: Anorexia; constipation; diarrhea; dry mouth; dyspepsia; flatulence; nausea; vomiting. GU: Decreased libido; dysuria; impotence; nocturia; urinary retention or frequency; urinary tract infection. HEPA: Elevated liver enzymes. META: May increase or decrease blood glucose. RESP: Bronchospasm; difficulty breathing; wheezing.
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