Information About Generic Azulfidine (Sulfasalazine)

What is Generic Azulfidine (Sulfasalazine)

Working of Generic Azulfidine (Sulfasalazine)

Generic Azulfidine (Sulfasalazine) Dosage or Administration

Precautions for Taking Generic Azulfidine (Sulfasalazine)

Interaction of Generic Azulfidine (Sulfasalazine) with Other Drugs

Side effects of Generic Azulfidine (Sulfasalazine)

Sulfasalazine is generic equivalent of Azulfidine, it is used for Treatment of ulcerative colitis; rheumatoid arthritis and juvenile rheumatoid arthritis (enteric-coated tablets). unlabeled use(s): Treatment of ankylosing spondylitis, collagenous colitis, Crohn disease, psoriasis, psoriatic arthritis.

What is Generic Azulfidine (Sulfasalazine)

Generic Azulfidine belong to calss Anti-infective/Sulfonamide. Generic Azulfidine Competitively antagonizes PABA, an essential component in folic acid synthesis.

Generic Azulfidine (Sulfasalazine) Dosage or Administration

ADULTS: PO 3 to 4 g/day in evenly divided doses. More than 4 g/day is associated with higher incidence of side effects. May begin with 1 to 2 g/day to lessen GI effects. Maintenance: 2 g/day in 4 divided doses. Children ³ 2 yrs: PO 40 to 60 mg/kg/24 hr initially in 3 to 6 divided doses. Maintenance: 20 to 30 mg/kg/day in 4 divided doses. Maximum 2 g/day.

Rheumatoid arthritis

ADULTS: PO Enteric-coated: 2 g/day in 2 evenly divided doses. May initiate therapy with a lower dosage (eg, 0.5 to 1 g/day) to reduce possible GI intolerance. Children ³ 6 yr: PO Enteric-coated 30 to 50 mg/kg/day in 2 evenly divided doses. Initiate therapy with 25% to 33% of the planned maintenance dose to lessen GI effects; increase weekly until reaching maintenance dose at 1 mo. Maximum 2 g/day.

Precautions for Taking Generic Azulfidine (Sulfasalazine)

Pregnancy: Category B. Lactation: Excreted in breast milk. Children: Do not use in infants < 2 mo. Allergy or asthma: Use drug with caution in patients with severe allergy or bronchial asthma. Hemolytic anemia may occur in G-6-PD deficient individuals. Contact lenses: May permanently stain soft contact lenses yellow. Porphyria: May precipitate acute attack of porphyria. Renal or hepatic impairment: Use drug with caution in patients with imparied renal or hepatic function. Severe reactions: Reactions, including deaths, have been associated with hypersensitivity reactions, agranulocytosis, aplastic anemia, other blood dyscrasias, and renal and hepatic damage.

Interaction of Generic Azulfidine (Sulfasalazine) with Other Drugs

Folic acid: Signs of folate deficiency have occurred, but specific symptoms related to deficiency have not been reported. Methotrexate: Risk of methotrexate-induced bone marrow suppression may be enhanced. Sulfonylureas: Increased sulfonylurea half-lives and hypoglycemia have occurred.

Side effects of Generic Azulfidine (Sulfasalazine)

CNS: Headache; insomnia; peripheral neuropathy; depression; convulsions. DERM: Orange-yellow discoloration of skin. GI: Nausea; vomiting; abdominal pain; diarrhea; anorexia; pancreatitis; impaired folic acid absorption; pseudomembranous enterocolitis. GU: Orange-yellow urine; crystalluria; hematuria; proteinuria; elevated creatinine; nephrotic syndrome; toxic nephrosis with oliguria and anuria.
generic viagra