Information About Generic Avodart (Dutasteride )

What is Generic Avodart (Dutasteride )

Working of Generic Avodart (Dutasteride )

Generic Avodart (Dutasteride ) Dosage or Administration

Precautions for Taking Generic Avodart (Dutasteride )

Interaction of Generic Avodart (Dutasteride ) with Other Drugs

Side effects of Generic Avodart (Dutasteride )

Dutasteride is generic equivalent of Avodart, it is used for treatment of male pattern baldness in men or Treatment of symptomatic benign prostatic hyperplasia in men with an enlarged prostate.

What is Generic Avodart (Dutasteride )

Generic Avodart belong to calss Androgen hormone inhibitor. Generic Avodart Inhibits the conversion of testosterone to 5-alpha-dihydrotestosterone, a potent androgen.

Generic Avodart (Dutasteride ) Dosage or Administration

Absorption: Tmax is 2 to 3 hr; bioavailability is approximately 60%; administration with food decreased Cmax 10% to 15%.

Distribution: Vd is 300 to 500 L; highly protein bound.

Metabolism: Metabolized by CYP3A4.

Elimination: Mainly excreted in feces (approximately 5% as unchanged dutasteride and approximately 40% as metabolites). The t½ is approximately 5 wk.

Precautions for Taking Generic Avodart (Dutasteride )

Pregnancy: Category X. Lactation: Undetermined. Children: Safety and efficacy not established. Hepatic impairment: Use with caution. Obstructive uropathy: Carefully monitor patients with large residual urine volume or severely diminished urinary flow.

Interaction of Generic Avodart (Dutasteride ) with Other Drugs

Cytochrome P450 3A4 inhibitors (eg, cimetidine, ciprofloxacin, diltiazem, ketoconazole, ritonavir, verapamil): Plasma concentrations of dutasteride may be elevated, increasing the risk of side effects.

Side effects of Generic Avodart (Dutasteride )

GU: Impotence; decreased libido; ejaculation disorder; gynecomastia.