Information About Generic Avapro (Irbesartan)

What is Generic Avapro (Irbesartan)

Working of Generic Avapro (Irbesartan)

Generic Avapro (Irbesartan) Dosage or Administration

Precautions for Taking Generic Avapro (Irbesartan)

Interaction of Generic Avapro (Irbesartan) with Other Drugs

Side effects of Generic Avapro (Irbesartan)

Irbesartan is generic equivalent of Avapro, it is used for Treatment of hypertension

What is Generic Avapro (Irbesartan)

Generic Avapro belong to calss Antihypertensive. Generic Avapro Antagonizes the effect of angiotensin II (vasoconstriction and aldosterone secretion) by blocking the angiotensin II (AT1 receptor) in vascular smooth muscle and the adrenal gland, producing decreased BP.

Generic Avapro (Irbesartan) Dosage or Administration

Hypertension

Adults: PO Start with 150 mg once daily; then titrate to 300 mg once daily as necessary.

Children (13 to 16 yr): PO Start with 150 mg once daily; then titrate patients requiring a further reduction in BP to 300 mg once daily.

Children (6 to 12 yr): PO Start with 75 mg once daily; then titrate patients requiring a further reduction in BP to 150 mg once daily.

Nephropathy in Type 2 Diabetes

Adults PO Titrate dose to 300 mg once daily.

Volume- and Salt-Depleted Patients

PO Start with 75 mg.

Precautions for Taking Generic Avapro (Irbesartan)

Pregnancy: Category C (first trimester); Category D (second and third trimesters). Can cause injury or death to the fetus if used during second or third trimester. Lactation: Undetermined. CHILDREN: Safety and efficacy not established in children younger than 6 yr. Renal function impairment: Use with caution in patients whose renal function may depend on the activity of the renin-angiotensin-aldosterone system (eg, patients with severe CHF); use may be associated with oliguria, progressive azotemia, acute renal failure, and death. Hypotension: Initiation of antihypertensive therapy may cause symptomatic hypotension in patients with intravascular volume or sodium-depletion.

Interaction of Generic Avapro (Irbesartan) with Other Drugs

Lithium: Plasma concentrations my be increased by irbesartan, resultingin an increase in the pharmacologic and adverse effects of lithium.

Side effects of Generic Avapro (Irbesartan)

CARDIOVASCULAR: Chest pain; tachycardia; edema. CNS: Headache; anxiety/nervousness; dizziness. GI: Diarrhea; dyspepsia/heartburn; abdominal pain; nausea/vomiting. RESPIRATORY: Upper respiratory infection; influenza; pharyngitis; rhinitis; sinus abnormality OTHER: Musculoskeletal pain/trauma; fatigue; UIT; rash.