Information About Generic Avandamet (Metformin and Rosiglitazone)

What is Generic Avandamet (Metformin and Rosiglitazone)

Working of Generic Avandamet (Metformin and Rosiglitazone)

Generic Avandamet (Metformin and Rosiglitazone) Dosage or Administration

Precautions for Taking Generic Avandamet (Metformin and Rosiglitazone)

Interaction of Generic Avandamet (Metformin and Rosiglitazone) with Other Drugs

Side effects of Generic Avandamet (Metformin and Rosiglitazone)

Metformin and Rosiglitazone is generic equivalent of Avandamet, it is used as an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus who are already treated with combination rosiglitazone and metformin or who are not adequately controlled on metformin alone.

What is Generic Avandamet (Metformin and Rosiglitazone)

Generic Avandamet belong to calss Antidiabetic combination, Thiazolinedione, Biguanide. Generic avandamet Increases insulin sensitivity; metformin: decreases blood glucose by reducing hepatic glucose production and may decrease intestinal absorption of glucose and increase response to insulin.

Generic Avandamet (Metformin and Rosiglitazone) Dosage or Administration

Base dosage selection of rosiglitazone and metformin on the patient's current doses of rosiglitazone or metformin (max, 8 mg rosiglitazone/2000 mg metformin/day).

Precautions for Taking Generic Avandamet (Metformin and Rosiglitazone)

Pregnancy Category C. Lactation Undetermined. Children Safety and efficacy not established. Elderly In general, elderly patients are not titrated to the maximum dose because of age-related decreases in renal function. Cardiac failure Fluid retention, which may exacerbate or lead to heart failure, may occur. Hepatic disease Avoid metformin in patients with clinical or laboratory evidence of hepatic disease. Iodinated contrast materials Metformin therapy should be withheld at the time of or prior to parenteral contrast studies with iodinate materials.

Interaction of Generic Avandamet (Metformin and Rosiglitazone) with Other Drugs

Alcohol The effects of metformin on lactate metabolism may be potentiated. Calcium channel blocking agents, corticosteroids, estrogens, isoniazid, nicotinic acid, oral contraceptives, phenothiazines, phenytoin, sympathomimetics, thiazides and other diuretics, thyroid products: These agents tend to produce hyperglycemia and may lead to loss of blood glucose control. Furosemide Metformin plasma levels may be elevated while furosemide levels may be decreased. Nifedipine Metformin plasma levels may be increased.

Side effects of Generic Avandamet (Metformin and Rosiglitazone)

CARDIOVASCULAR: Cardiac failure. CNS: Headache; fatigue. EENT: Sinusitis. GI: Diarrhea. HEMATOLOGIC: Anemia. RESPIRATORY: Upper respiratory tract infection; pulmonary edema; pleural effusions. OTHER: Injury; back pain; viral infection; arthralgia; edema.