Information About Generic Augmentin (Amoxicillin/Clavulanate Potassium)

What is Generic Augmentin (Amoxicillin/Clavulanate Potassium)

Working of Generic Augmentin (Amoxicillin/Clavulanate Potassium)

Generic Augmentin (Amoxicillin/Clavulanate Potassium) Dosage or Administration

Precautions for Taking Generic Augmentin (Amoxicillin/Clavulanate Potassium)

Interaction of Generic Augmentin (Amoxicillin/Clavulanate Potassium) with Other Drugs

Side effects of Generic Augmentin (Amoxicillin/Clavulanate Potassium)

Amoxicillin/Clavulanate Potassium is generic equivalent of Augmentin, it is used for Treatment of infections caused by susceptible strains of microorganisms.

What is Generic Augmentin (Amoxicillin/Clavulanate Potassium)

Generic Augmentin belong to calss Aminopenicillin. Generic Amoxicillin/Clavulanate Potassium Amoxicillin inhibits bacterial cell wall mucopeptide synthesis. Clavulanic acid inactivates a wide range of beta-lactam enzymes found in bacteria resistant to penicillins and cephalosporins.

Generic Augmentin (Amoxicillin/Clavulanate Potassium) Dosage or Administration

Augmentin

Strength listed below is based on amoxicillin content.

ADULTS AND CHILDREN OVER 12 YR: PO One 500 mg tablet q 12 hr or one 250 mg tablet q 8 hr (500 and 250 mg tablets contain the same amount of clavulanate. Thus two 250 mg tablets are not equivalent to one 500 mg tablet.)

Severe Infections

PO 500 mg q 8 hr; 875 mg q 12 hr.

CHILDREN UNDER 3 MO: PO Elimination impaired in children under 3 mo. 30 mg/kg/day divided q 12 hr. CHILDREN OVER 3 YR: PO For otitis media, sinusitis, lower respiratory tract infections, severe infections, 45 mg/kg/day if given q 12 hr; 40 mg/kg/day if given q 8 hr. LESS SEVERE INFECTIONS FOR CHILDREN: PO 25 mg/kg/day if given q 12 hr; 20 mg/kg/day if given q 8 hr.

Augmentin ES-600

Augmentin ES-600 (5 mL) does not contain the same amount of clavulanic acid as any of the other Augmentin suspensions (5 mL). Therefore, Augmentin ES-600 and Augmentin are not interchangeable. The dose listed below is based on the amoxicillin component. CHILDREN 3 MO AND OLDER: PO 90 mg/kg/day divided q 12 hr for 10 days.

Precautions for Taking Generic Augmentin (Amoxicillin/Clavulanate Potassium)

Pregnancy: Category B. Children: Safety and efficacy of Augmentin ES-600 in children weighing 40 kg or more not established. Adults: Safety and efficacy of Augmentin ES-600 not established. Lactation: Secreted into breast milk. Mononucleosis patients: Increased risk of skin rash. Use not recommended. Phenylalanine: Contains phenylalanine. 200 and 400 mg chewable tablets, 200 mg/5 mL and 400 mg/5 mL only. Renal: Dose reduction or q 12 hr recommended with severe impairment. Hepatic: Use with caution.

Interaction of Generic Augmentin (Amoxicillin/Clavulanate Potassium) with Other Drugs

Allopurinol: May increase incidence of rash. Contraceptives, oral: May reduce effectiveness of oral contraceptives. Probenecid: May increase and prolong blood levels of amoxicillin. Tetracyclines: May reduce antibacterial effectiveness of amoxicillin.

Side effects of Generic Augmentin (Amoxicillin/Clavulanate Potassium)

CNS: Dizziness; fatigue; insomnia; reversible hyperactivity. DERM: Erythema multiforme; maculopapular to exfoliative dermatitis; skin rashes; vesicular eruptions; urticaria. EENT: Abnormal taste sensation; black “hairy” tongue; glossitis; itchy eyes; laryngeal edema; laryngospasm; sore or dry mouth or tongue; stomatitis. GI: Abdominal pain or cramps; anorexia; diarrhea or bloody diarrhea; enterocolitis; epigastric distress; flatulence; gastritis; nausea; pseudomembranous colitis; rectal bleeding; vomiting.