Information About Generic Anaprox (Perindopril erbumine)

What is Generic Anaprox (Perindopril erbumine)

Working of Generic Anaprox (Perindopril erbumine)

Generic Anaprox (Perindopril erbumine) Dosage or Administration

Precautions for Taking Generic Anaprox (Perindopril erbumine)

Interaction of Generic Anaprox (Perindopril erbumine) with Other Drugs

Side effects of Generic Anaprox (Perindopril erbumine)

Canonical to aleve

Perindopril erbumine is generic equivalent of Anaprox, it is used for Rx: Management of mild to moderate pain, symptoms of rheumatoid or osteoarthritis, bursitis, tendonitis, ankylosing spondylitis, primary dysmenorrhea, acute gout. Naproxen (not naproxen sodium) also indicated for treatment of juvenile rheumatoid arthritis. Delayed-release naproxen is not recommended for initial treatment of acute pain because absorption is delayed compared to other naproxen formulations. OTC: Temporary relief of minor aches and pains associated with the common cold, headache, toothache, muscular aches, backache, minor arthiritis pain, pain of menstrual cramps, and reduction of fever. unlabeled use(s): Sunburn, migraine, PMS.

What is Generic Anaprox (Perindopril erbumine)

Generic Anaprox belong to calss Analgesic/NSAID. Generic Perindopril erbumine Decreases inflammation, pain and fever, probably through inhibition of cyclooxygenase activity and prostaglandin synthesis.

Generic Anaprox (Perindopril erbumine) Dosage or Administration

Rheumatoid Arthritis, Osteoarthritis, Ankylosing Spondylitis

ADULTS: PO 250 to 500 mg bid; maximum dose of 1.5 g/day should be used short term only. Delayed-release: PO 375 to 500 mg twice/day. Controlled release: PO 750 to 1000 mg once daily. Individualize dosage. Do not exceed 1500 mg/day. Suspension: PO 250 mg (10 mL), 375 mg (15 mL), or 500 mg (20 mL) twice daily.

Pain, Dysmenorrhea, Bursitis, Tendinitis

ADULTS: PO 500 mg initially, then 250 mg q 6 to 8 hr. Do not exceed 1250 mg/day.

Juvenile Rheumatoid Arthritis

CHILDREN: PO 10 mg/kg/day in 2 divided doses. For children requiring suspension, 2.5 mL bid can be given for weights of ³ 13 kg; 5 mL bid for weights of ³ 25 kg, or 7.5 mL bid for weights of ³ 38 kg.

Acute Gout

ADULTS: PO 750 mg, followed by 250 mg q 8 hr until the attack subsides.

Naproxen Sodium

Rheumatoid Arthritis, Osteoarthritis, Ankylosing Spondylitis

ADULTS: PO 275 to 550 mg bid. May increase to 1.65 g for limited perods.

Acute Gout

ADULTS: 825 mg initially, then 275 mg q 8 hr prn. Controlled-release: PO 1000 to 1500 mg once daily on the 1st day, then 1000 mg once daily until attack has subsided.

Pain, Dysmenorrhea, Tendinitis, Bursitis

ADULTS: PO 500 mg initially, then 275 mg q 6 to 8 hr prn. Do not exceed 1375 mg/day. Controlled release: PO 750 to 1000 mg once daily. Individualize dosage. Do not exceed 1500 mg/day.

Precautions for Taking Generic Anaprox (Perindopril erbumine)

Pregnancy: Category B. Lactation: Excreted in breast milk. Elderly patients: Increased risk of adverse reactions. Children: Rx: Safety and efficacy in children < 2 years of age have not been established. OTC: Do not give to children < 12 years of age except under the advice and supervision of a physician. Cardiovascular disease: Drug may worsen CHF and may decrease hypertension control. Concomitant therapy: Do not use naproxen sodium and naproxen concomitantly; both drugs circulate as naproxen anion. GI effects: Serious GI toxicity (eg, bleeding, ulceration, perforation) can occur at any time, with or without warning symptoms. Hepatic impairment: May need to reduce dose. Renal impairment: Assess function before and during therapy because NSAID metabolites are eliminated renally.

Interaction of Generic Anaprox (Perindopril erbumine) with Other Drugs

Anticoagulants: May increase effect of anticoagulants because of decreased plasma protein binding. May increase risk of gastric erosion and bleeding. Lithium: May decrease lithium clearance. Methotrexate: May increase methotrexate levels.

Side effects of Generic Anaprox (Perindopril erbumine)

CV: Edema; weight gain; congestive heart failure; alterations in blood pressure; vasodilation; palpitations; tachycardia; chest pain; bradycardia. CNS: Headache; dizziness; drowsiness; vertigo; lightheadedness; mental depression; nervousness; irritability; fatigue; malaise; insomnia; sleep disorders; dream abnormalities; aseptic meningitis. DERM: Rash; urticaria; purpura; skin eruptions. EENT: Visual changes; tinnitus; rhinitis; pharyngitis, stomatitis. GI: Constipation; heartburn; abdominal pain; peptic ulceration and bleeding; nausea; dyspepsia; diarrhea; vomiting; anorexia; colitis; flatulence. GU: Glomerulonephritis; interstitial nephritis; nephrotic syndrome; acute renal insufficiency and renal failure; dysuria; hyperkalemia; hyponatremia; renal papillary necrosis. HEPA: Increased liver function test results. HEMA: Increased bleeding time; leukopenia; thrombocytopenia; granulocytopenia; eosinophilia; ecchymosis. RESP: Bronchospasm; laryngeal edema; dyspnea; shortness of breath.