Information About Generic Amiloride (Amiloride)

What is Generic Amiloride (Amiloride)

Working of Generic Amiloride (Amiloride)

Generic Amiloride (Amiloride) Dosage or Administration

Precautions for Taking Generic Amiloride (Amiloride)

Interaction of Generic Amiloride (Amiloride) with Other Drugs

Side effects of Generic Amiloride (Amiloride)

Amiloride is generic equivalent of Amiloride, it is used for Treatment of CHF or hypertension (in combination with thiazide or loop diuretics) and diuretic-induced hypokalemia. Unlabeled use(s): Reduction of lithium-induced polyuria. Aerosol form: Slowed reduction of pulmonary function in patients with cystic fibrosis.

What is Generic Amiloride (Amiloride)

Generic Amiloride belong to calss Potassium-sparing diuretic. Generic Amiloride Interferes with sodium reabsorption at distal tubule, resulting in increased excretion of water and sodium and decreased excretion of potassium.

Generic Amiloride (Amiloride) Dosage or Administration

ADULTS: PO 5 to 10 mg daily. LITHIUM-INDUCED POLYURIA: PO 10 to 20 mg daily. CYSTIC FIBROSIS: Dissolve in 0.3% saline and deliver by nebulizer.

Precautions for Taking Generic Amiloride (Amiloride)

Pregnancy: Category B. Lactation: Undetermined. Children: Safety and efficacy not established. Diabetes mellitus: Hyperkalemia may occur. Electrolyte imbalances and BUN increase: Hyperkalemia, hyponatremia, hypochloremia, and increases in BUN may occur. Hepatic impairment: With severe liver disease, hepatic encephalopathy (eg, tremors, confusion, coma, jaundice) may occur. Renal impairment: Use cautiously in patients with this condition.

Interaction of Generic Amiloride (Amiloride) with Other Drugs

Angiotensin-converting enzyme inhibitors: May result in severely elevated serum potassium levels. Potassium preparations: May severely increase serum potassium levels, possibly resulting in cardiac arrhythmias or cardiac arrest. Do not administer to patients taking potassium preparations.

Side effects of Generic Amiloride (Amiloride)

CV: Angina pectoris; orthostatic hypotension; arrhythmia. CNS: Headache; dizziness; encephalopathy; paresthesia; tremors; vertigo; nervousness; mental confusion; insomnia; decreased libido; depression. DERM: Skin rash; itching; pruritus. EENT: Visual disturbances; tinnitus; nasal congestion. GI: Nausea; anorexia; diarrhea; vomiting; abdominal pain; gas pain; appetite changes; constipation; GI bleeding; abdominal fullness; thirst; dry mouth; heartburn; flatulence. GU: Impotence; polyuria; dysuria; urinary frequency. HEMA: Aplastic anemia; neutropenia. HEPA: Jaundice. META: Increased serum potassium levels. RESP: Cough; dyspnea. OTHER: Musculoskeletal (weakness; fatigue; muscle cramps; joint/back/chest pain; neck or shoulder ache).
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