Information About Generic Aciphex (Rabeprazole)

What is Generic Aciphex (Rabeprazole)

Working of Generic Aciphex (Rabeprazole)

Generic Aciphex (Rabeprazole) Dosage or Administration

Precautions for Taking Generic Aciphex (Rabeprazole)

Interaction of Generic Aciphex (Rabeprazole) with Other Drugs

Side effects of Generic Aciphex (Rabeprazole)

Rabeprazole is generic equivalent of Aciphex, it is used to treat Short-term treatment in healing and symptomatic relief of duodenal ulcers and erosive or ulcerative gastroesophageal reflux disease (GERD); maintaining healing and reducing relapse rates of heartburn symptoms in patients with GERD; treatment of daytime and nighttime heartburn and other symptoms associated with GERD; long-term treatment of pathological hypersecretory conditions, including Zollinger-Ellison syndrome in combination with amoxicillin and clarithromycin to eradicate H. pylori.

What is Generic Aciphex (Rabeprazole)

Generic Rabeprazole belong to calss Gastrointestinal, Proton Pump Inhibitor. Generic Rabeprazole Suppresses gastric acid secretion by blocking “acid (proton) pump” within gastric parietal cells.

Generic Aciphex (Rabeprazole) Dosage or Administration

Treatment of Erosive or Ulcerative GERD

Adults: PO 20 mg/day for 4 to 8 wk, an additional 8 wk may be considered for patients who do not heal.

Maintenance of Erosive or Ulcerative GERD

Adults: PO 20 mg/day.

Healing of Duodenal Ulcers

Adults: PO 20 mg/day after the morning meal for 4 wk, additional therapy may be required for some patients.

Treatment of Pathological Hypersecretory Conditions

Adults: PO 60 mg/day. Doses up to 100 mg qd or 60 mg bid have been administered.

H. Pylori Eradication to Reduce Risk of Duodenal Ulcer Recurrence

Adults: PO 20 mg rabeprazole plus amoxicillin 1000 mg plus clarithromycin 500 mg bid for 7 days with morning and evening meals.

Precautions for Taking Generic Aciphex (Rabeprazole)

Pregnancy: Category B. Lactation: Undetermined. Children: Safety and efficacy not established. Gastric malignancy: Symptomatic response to rabeprazole does not preclude gastric malignancy.

Interaction of Generic Aciphex (Rabeprazole) with Other Drugs

Drugs dependent on gastric pH for absorption (eg, digoxin, ketoconazole): Plasma levels of digoxin may be increased, while ketoconazole concentrations may be decreased.

Side effects of Generic Aciphex (Rabeprazole)

CARDIOVASCULAR: Hypertension; MI; ECG abnormalities; migraine; syncope; angina pectoris; bundle branch block; palpitation; sinus bradycardia; tachycardia. CNS: Headache; insomnia; anxiety; dizziness; depression; nervousness; somnolence; hypertonia; neuralgia; vertigo; convulsion; extrapyramidal syndrome; hyperkinesias. DERMATOLOGIC: Rash; pruritus; sweating; urticaria; alopecia. EENT: Cataract; amblyopia; glaucoma; dry eyes; abnormal vision; tinnitus; otitis media. GI: Diarrhea; nausea; abdominal pain; vomiting; dyspepsia; flatulence; constipation; dry mouth; eructation; gastroenteritis; rectal hemorrhage; melena; anorexia; mouth ulceration; stomatitis; dysphagia; gingivitis; increased appetite; abnormal stools; proctitis; colitis; esophagitis; glossitis; pancreatitis; cholelithiasis; cholecystitis. GU: Cystitis; urinary frequency; dysmenorrhea; dysuria; kidney calculus; metrorrhagia; polyuria. HEMATOLOGIC: Anemia; ecchymosis; lymphadenopathy; hypochromic anemia. METABOLIC: Hyperthyroidism; hypothyroidism; peripheral edema; edema; weight gain/loss; gout; dehydration. RESPIRATORY: Dyspnea; asthma; epistaxis; laryngitis; hiccough; hyperventilation. OTHER: Asthenia; fever; allergic reaction; chills; malaise; substernal chest pain; neck rigidity; photosensitivity reaction; myalgia; arthritis; leg cramps; bone pain; arthrosis; bursitis.
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